Aging and Testosterone Levels
Men with hypogonadism have low levels of testosterone (low t) and accompanying symptoms, which may include a decrease in sexual desire, erectile
dysfunction
, reduced muscle mass and strength, a reduction in bone density, changes in mood, and/or an increase in fat mass. If hypogonadism occurs in aging men, it is called late onset symptomatic hypogonadism or andropause. Hypogonadism can occur in younger men who have a testicular disorder (primary hypogonadism) or a disorder of the neuroendocrine system (secondary hypogonadism). These disorders can develop as a result of disease, heroin and cocaine abuse, or other factors.
Aging is one of the main causes of low testosterone in men. As men reach their 40s, their testosterone levels gradually drop by one or two percent each year, though some men may begin losing testosterone earlier in life. Testosterone loss can also be a side effect of another underlying condition, such as obesity or chronic kidney disease, so you may want to get a physical exam to determine the root cause of your low testosterone (t) levels. Our facility offers multiple treatments to help men increase their t levels, which we can discuss in your first appointment.
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Low Testosterone and the Body
Dht (dihydrotestosterone) is a hormone that plays a key role in the sexual development of people assigned male at birth (amab).
More specifically, dht is an androgen — a hormone that stimulates the development of male characteristics. Dht affects the sexual development of people amab throughout their lives, beginning as early as in fetal development. The role of dht changes as people amab progress through different life stages. Scientists aren’t sure if and how dht affects people assigned female at birth (afab), but they think it may play a role in body hair and pubic hair growth. As an adult, your body converts about 10% of your testosterone (the main androgen) into dht each day.
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Medically reviewed by vicky davis, fnp written by our editorial team last updated 11/17/2022
men who have low testosterone do not make enough of the male hormone called testosterone. This hormone allows men to produce sperm and to develop and keep normal physical male traits. Low testosterone is also called testosterone deficiency or hypogonadism. Low testosterone can lead to problems such as loss of sex drive, erection problems, infertility, and weakened bones. https://t.co/kyUafIi9aW
Testosterone has effects on many organs and systems. The purpose of this study was to test the hypothesis that low testosterone is associated with changes in various non-cardiovascular biomarkers in men older than 40 who were tested for possible hypogonadism. We extracted data from 9939 outpatient men who were over 40 years old (median age 56) and who also had concurrent laboratory measurements of total testosterone and one or more biomarkers of interest: estradiol, uric acid, prostate-specific antigen (psa), sex-hormone binding globulin (shbg), luteinizing hormone, creatinine, bone alkaline phosphatase (bap), creatine kinase, hemoglobin a1c, and 25-hydroxy-vitamin d, and body mass index (bmi).